(WASHINGTON) — Tuesday marks five years since the World Health Organization (WHO) declared the global outbreak of COVID-19 to be a pandemic.
Since then, millions of Americans have been hospitalized, and more than 1.2 million people have died.
Additionally, millions of adults and children are still feeling the effects of their illness and have been diagnosed with long COVID.
Here’s a look at the disease in the U.S. by the numbers.
Hospitalizations
In the last 28 days, ending about Feb. 16, 2025, about 3,800 Americans were hospitalized due to COVID-19, according to data from the WHO.
During the week ending Feb. 22, the most recent week for which data is available, data from the Centers for Disease Control and Prevention (CDC) shows that just 1.3% of inpatient beds were occupied by COVID-19 patients as well as 1.3% of intensive care unit beds.
Additionally, during the week ending March 1, the rate of COVID-19-associated hospitalizations was 1.4 per 100,000 people. The peak for the 2024-25 season was 4.2 per 100,000 people during the week ending Jan. 4, which is much lower than the peak of 35.6 per 100,000 people during the 2021-22 season.
Deaths
Since the pandemic began, more than 1.22 million Americans have died from COVID-19 as of March 6, 2025, according to the latest CDC data. The U.S. crossed the 1 million mark on May 12, 2022.
During the week ending March 1, there were 274 deaths recorded from COVID, according to CDC provisional data. This is the lowest number recorded since the pandemic began.
Meanwhile, the age-adjusted death rate currently sits at 0.1 per 100,000 people, which has remained relatively consistent since spring 2024 and is among the lowest rates recorded since the pandemic.
By comparison, during the height of the omicron wave in winter 2021-22, the death rate was 53 times higher at 5.3 per 100,000. The highest-ever death rate was recorded the week ending Jan. 9, 2021, at 6.5 per 100,000.
Studies have suggested COVID-19 vaccines, combined with mitigation measures, helped save hundreds of thousands of lives in the U.S.
Long COVID
Long COVID is a condition that occurs when someone infected with COVID-19 is within three months of the initial diagnosis and lasts at least two months.
As of August 2024, a federal survey found that 17.9% of adults have experienced long COVID — equivalent to about 47.6 million Americans, according to 2024 U.S. Census Bureau estimates.
Meanwhile, 5.3% of adults — equivalent to about 14.1 million Americans — reported they were currently experiencing long COVID symptoms at the time of the survey. Of those currently experiencing long COVID, nearly a quarter said they had significant activity limitations.
Another recent federal study, published in the journal JAMA Pediatrics in February, showed approximately 1.01 million children, or 1.4%, are believed to have ever experienced long COVID as of 2023 and about 293,000, or 0.4%, were experiencing the condition when the survey was being conducted.
Vaccines
In June 2024, the CDC recommended that everyone ages 6 months and older receive an updated 2024-2025 COVID-19 vaccine to protect against severe illness, hospitalization and death.
The updated vaccines target the JN.1 lineage of the virus, an offshoot of the omicron variant. There are formulations from Pfizer-BioNTech and Moderna available for those 6 months old and older and from Novavax available for those aged 12 and older.
The CDC, however, has previously stated vaccination coverage remains low, meaning “many children and adults lack protection from respiratory virus infections provided by vaccines.”
As of Feb. 22, 2025, only 23.2% of adults and 11.9% of children were vaccinated with the updated vaccine, CDC data shows.
Additionally, despite evidence showing the vaccine is safe for pregnant women, the CDC estimates that just 13.8% of pregnant women have received the updated vaccine.
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